Scientists develop synthetic CBD for seizure treatments


Cannabidiol (CBD) is a cannabis compound thought to have many health benefits to humans and animals alike. It acts through a specific mechanism that exists in the body, called the endocannabinoid system, and possesses strong anti-inflammatory, anti-bacterial, and analgesic properties, among others.

Moreover, particularly in the brain, CBD can act as a powerful suppressant of psychotic episodes, a mood stabilizer, and an effective anti-seizure substance.

Given these properties, the benefits of using CBD in psychiatric disorders are very well known and preferred by many patients. There is even an FDA-approved CBD-based medication already in the market.

However, due to the concerns surrounding the safety of cannabis and cannabis-derived products (therefore leading to unclear legislation and difficulty in approval by regulatory agencies), there aren’t yet that many permitted uses for CBD in the US and EU.

This issue is especially sensitive because, given the right tools, methods, and environment, cannabis-derived CBD can be transformed into tetrahydrocannabinol (also called THC), a known psychoactive substance that is prohibited in many countries.

To try and bypass this problem, scientists developed a compound named 8,9-dihydrocannibidiol (H2CBD), which has the same structure as CBD but is entirely synthetic.

According to the researchers, H2CBD can have the same anti-convulsant effects as CBD and can be used in the exact same ways. Moreover, and since it’s synthetic and not a controlled substance, H2CBD has other attractive and positive traits:

  • It can be used in CBD-based therapies without being subjected to anti-cannabis laws and regulations;
  • Since it’s not extracted from the cannabis plant, it can be obtained in its most pure form, without incurring the risk of being contaminated by pesticides or other compounds;
  • It may eliminate the need for cultivating, importing, or processing cannabis plants;
  • It can’t be transformed into THC.

Scientists also refer that H2CBD may be a safer, equally efficient, inexpensive, and scalable substitute for CBD, but require more studies to fully assess how the synthetic substance works and what impacts it may have on the body.

Given the complex history, laws, and regulations surrounding cannabis and CBD-based therapies, specialists believe that H2CBD may be a valid and safe alternative that can work just as well in preventing convulsions and seizures.

We will be covering the developments linked to H2CBD as more research is released in the coming months.


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